Cassiopeia Portrait
Cassiopeia
Patch 9.16 Mid Lane

Cassiopeia Build and Runes

Cassiopeia build guide, best Cassiopeia runes and items to use in Patch 9.16. This Cassiopeia Mid Lane build for LoL is based on win rates and meta popularity. Use this Cassiopeia build guide to statistically win more games in League.

Serpentine Grace
Noxious Blast
Miasma
Twin Fang
Petrifying Gaze

Games analyzed

53,182

Win %

50.02%

Pick %

2.88%

Ban %

2.47%

Kills

56.46

Deaths

80

Assists

87

Skill Priority (0 Games)

Twin Fang
Noxious Blast
Miasma
Noxious Blast
Miasma
Twin Fang
Petrifying Gaze
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Spells & Items

Summoner Spells

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Starting Build (Winrate)

Sapphire Crystal
Refillable Potion

End-game Build (Winrate)

Archangel's Staff
Rylai's Crystal Scepter
Demonic Embrace
Zhonya's Hourglass
Rabadon's Deathcap

Runes

Cassiopeia

Primary

Sorcery

Summon Aery
Arcane Comet
Phase Rush
Nullifying Orb
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
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Secondary

Domination

Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
Adaptive
AttackSpeed
CDRScaling
Adaptive
Armor
MagicRes
HealthScaling
Armor
MagicRes

Cassiopeia build in Patch 9.16

Find out the best Cassiopeia build by following the statistics on this page. You are more likely to perform better in your games by following this build.

The most winning Cassiopeia build involves a skill priority of Twin Fang Twin Fang Noxious Blast Noxious Blast Miasma Miasma , running a Sorcery | Domination rune set-up and taking Flash Flash Teleport Teleport as summoner spells.

Start your Cassiopeia build off by running Sapphire Crystal Sapphire Crystal Refillable Potion Refillable Potion , progressing that into Archangel's Staff Archangel's Staff Rylai's Crystal Scepter Rylai's Crystal Scepter Demonic Embrace Demonic Embrace Zhonya's Hourglass Zhonya's Hourglass Rabadon's Deathcap Rabadon's Deathcap , But remember to pick the correct situational items depending on game factors such as enemy composition.

Cassiopeia runes in Patch 9.16

Primary Runes

Here are the best Cassiopeia runes for this build. Take Summon Aery Summon Aery as your keystone in the Sorcery rune tree. The remaining slots in your primary tree should be the Manaflow Band Manaflow Band Transcendence Transcendence Scorch Scorch runes.

Secondary Runes

Cassiopeia's secondary runes should be in the Domination rune tree, taking the Taste of Blood Taste of Blood Ravenous Hunter Ravenous Hunter runes.

As far as your shards go, take CDRScalingCDRScaling AdaptiveAdaptive ArmorArmor . Following these runes for Cassiopeia will help you in your games. Make sure to make situational changes to your runes depending on team comps and counters.

While you're looking at our Cassiopeia build

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